Synovial Sarcoma:  A malignant sarcoma of soft tissue that arises near but not in a joint, most often in an adolescent or young adult, is typically slow-growing, and may escapes notice until it causes pain, usually after a sport injury. These tumors occur mainly in the arms or legs in the area of large joints, especially the knees. Less frequently, the disease develops in the head and neck or in the trunk. While the tumor is called synovial sarcoma (or synoviosarcoma), it has never been shown to arise from synovial cells (the cells that line a joint). It accounts for between 5 and 10 percent of the approximately 10,000 new soft tissue sarcomas reported each year.

The diagnosis of this tumor can be suspected by X-ray or imaging, made by biopsy, and confirmed by chromosome studies.

The most common treatment for the tumor is surgery to remove the entire tumor, nearby muscle, and lymph nodes. In rare cases, amputation may be necessary. Some patients have radiation, chemotherapy, or a combination of treatment methods. It is common for synovial cancer to recur, usually within the first two years after treatment. Half of the cases metastasize (spread to other areas of the body) to the lungs, lymph nodes, or bone marrow,  sometimes many years after the initial diagnosis. Patients with sarcoma are usually followed for a minimum of ten years.

Synovial Sarcomas  

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